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Fig. 5 | Clinical Sarcoma Research

Fig. 5

From: IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas

Fig. 5

Lower 5hmC levels in tumours with decreased nuclear staining for TET1. a There is no significant difference in subcellular localization of TET1 in IDH mutant versus IDH wildtype chondrosarcomas, and complete nuclear exclusion of TET1 was absent. b In tumours in which the staining was predominantly cytoplasmic, 5-hmC levels were significantly lower as compared to tumours in which staining was predominantly nuclear (scores were rounded to zero decimal places)

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Clinical Sarcoma Research

ISSN: 2045-3329