Local treatment modality | Subdivision of RT and surgery group | ||||
---|---|---|---|---|---|
Radiotherapy (RT) alone N = 108 | Surgery alone N = 119 | RT and surgery N = 221 | RT then surgery N = 152 | Surgery then RT N = 69 | |
No. events | |||||
EFS | 62 | 42 | 83 | 61 | 22 |
OS | 53 | 33 | 66 | 49 | 17 |
Unadjusted | |||||
EFS | 0.89 (0.54–1.46) | 1.44 (0.78–2.64) | 1.66 (0.94–2.96) | 2.44 (0.76–7.81) | 2.36 (1.02–5.45) |
OS | 0.99 (0.56–1.64) | 1.74 (0.86–3.51) | 1.60 (0.84–3.06) | 2.70 (0.84–8.73) | 2.03 (0.78–5.28) |
Adjusted for age, primary site and histology | |||||
EFS | 0.98 (0.58–1.66) | 1.51 (0.78–2.94) | 1.65 (0.91–2.99) | 2.39 (0.71–8.05) | 2.12 (0.83–5.40) |
OS | 1.10 (0.62–1.95) | 1.94 (0.89–4.25) | 1.50 (0.77–2.93) | 3.10 (0.90–10.70) | 1.74 (0.60–5.08) |
Adjusted for age, primary site, histology and time between the start of chemotherapy and starting local treatment | |||||
EFS | 0.95 (0.54–1.67) | 1.48 (0.76–2.89) | 1.48 (0.81–2.69) | 1.69 (0.50–5.68) | 2.10 (0.82–5.41) |
OS | 1.03 (0.55–1.90) | 1.92 (0.87–4.24) | 1.39 (0.71–2.74) | 2.49 (0.72–8.58) | 1.74 (0.59–5.10) |