Skip to main content

Table 1 Patient samples treated with 5 gy of radiation

From: Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes

Sample

Grade

IDH mutation status

Other alterations

Mean + SEM basic foci level

Mean + SEM after 5gy radiation

Difference between means

P value

L5213

1

WT

 

3.053 ± 0.6277

n = 38

14.28 ± 1.737

n = 32

11.23 ± 1.733

< 0.0001

L5678

3

IDH1 R132C

 

0.2295 ± 0.07165

n = 61

8.239 ± 1.477

n = 46

8.01 ± 1.284

< 0.0001

L5676

2

IDH2 R172S

 

3.625 ± 0.9297

n = 32

9 ± 1.493

n = 34

5.375 ± 1.784

0.003712

L5541

Dediff

IDH1 R132S

 

2.378 ± 0.5747

n = 90

6.702 ± 1.225

n = 57

4.324 ± 1.212

0.0005

L5546

2

WT

CDKN2A deletion

3.982 ± 0.9036

n = 56

6.846 ± 1.172

n = 52

2.864 ± 1.468

0.0537

L5302

3

WT

CDKN2A deletion

2.246 ± 0.4531

n = 61

5.082 ± 0.7412

n = 73

2.836 ± 0.9108

0.0023

  1. Foci were counted 2 h after treatment