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Table 2 Patient samples treated with 5 gy of radiation

From: Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes

Sample

Grade

IDH mutation status

Other alterations

Mean + SEM basic foci level

Mean + SEM after 5gy radiation

Difference between means

P value

L5847

2

WT

 

2.644 ± 0.7399

n = 59

7.467 ± 1.526

n = 30

4.823 ± 1.501

0.0018

L5718

3

IDH1 R132L

CDKN2A deletion

2.437 ± 0.584

n = 87

4.088 ± 0.6256

n = 102

1.651 ± 0.8659

0.0580

L5850

2

WT

RB1 deletion

0.6327 ± 0.1409

n = 98

1.55 ± 0.1809

n = 140

0.9173 ± 0.2463

0.0002

  1. Foci were counted 24 h after treatment
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Clinical Sarcoma Research

ISSN: 2045-3329