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Fig. 2 | Clinical Sarcoma Research

Fig. 2

From: A rare presentation of carcinosarcoma of the bone in a young female; response with gemcitabine and docetaxel

Fig. 2

Staining of Specimens. Histopathologic features of the T9 biopsy and intraoperative femur stabilization specimens, indicated in lower right corners. A Nests of osteoid producing cells can be seen surrounded by swirls of pleomorphic spindle cells and reticular substance. HE ×40. B The tumor is predominantly made up of irregular spindle cells. HE ×40. C The tumor can be seen infiltrating normal bone architecture, HE ×40. D Pleomorphic spindle cells with intervening stroma. HE ×200. E Poorly defended clusters of cells can be seen surrounded by neoplastic stroma, HE ×200. F Spindle cells showing a high degree of pleomorphism, hyperchromatic nuclei, and irregular nuclear contours. HE ×200. G Positive immunohistochemical staining for OSCAR cytokeratin in scattered spindle cells, ×200. H Scattered positive immunohistochemical staining for OSCAR cytokeratin, ×200. I The same scattered positive immunohistochemical staining for OSCAR cytokeratin is seen in the femur biopsy, ×200

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