Fig. 2

Clinical outcomes for localized soft tissue sarcomas with genomic sequencing treated at Stanford (n = 96). a Forest plot of most commonly altered 8 genes with prognosis reveals only CDKN2A to be significantly associated with worse prognosis. b Kaplan–Meier plot of overall survival for CDKN2A altered vs. non-CDKN2A altered patients (p = 0.017). c Histologic distribution of all patients (d) and CDKN2A altered patients (C2) reveals increases in representation of MPNST, MFS, and UPS with decreases in LMS and LPS. e Kaplan–Meier plot of time to recurrence for CDKN2A altered vs. non-CDKN2A altered patients (p = 0.09). f Kaplan–Meier plot of time to treatment failure for first line systemic chemotherapy for CDKN2A altered vs. non-CDKN2A altered patients (p = 0.29)