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Table 2 Cox proportional hazard regression models for disease-free survival

From: Anthracycline-based and gemcitabine-based chemotherapy in the adjuvant setting for stage I uterine leiomyosarcoma: a retrospective analysis at two reference centers

Characteristic Univariable model Multivariable model
HR (95% CI) P HR (95% CI) P
Age (years) 1.07 (0.84–1.35)b 0.59
Stage
 IB vs IA 1.99 (0.98–4.03) 0.06 4.27 (1.28–14.20) 0.02
Mitotic index
 a34 vs 12 1.02 (1.00–1.03) 0.07 1.01 (0.99–1.03) 0.22
Surgery
 LPS vs LPT 0.82 (0.35–1.89) 0.64
Morcellation
 Yes vs No 1.01 (0.51–2.01) 0.98
Oophorectomy
 Yes vs No 0.92 (0.53–81.60) 0.78
RT
 Yes vs No 0.68 (0.29–1.58) 0.37
Regimen
 A based vs G based 0.49 (0.30–0.80) 0.004 0.37 (0.17–0.80) 0.01
  1. aThe reported values are the third and first quartiles of the variable distribution
  2. bHazard ratio for a 10 years increase in age
  3. HR hazard ratio, CI confidence interval, G gemcitabine, A anthracycline, RT radiotherapy