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Table 2 Cox proportional hazard regression models for disease-free survival

From: Anthracycline-based and gemcitabine-based chemotherapy in the adjuvant setting for stage I uterine leiomyosarcoma: a retrospective analysis at two reference centers

Characteristic

Univariable model

Multivariable model

HR (95% CI)

P

HR (95% CI)

P

Age (years)

1.07 (0.84–1.35)b

0.59

–

–

Stage

 IB vs IA

1.99 (0.98–4.03)

0.06

4.27 (1.28–14.20)

0.02

Mitotic index

 a34 vs 12

1.02 (1.00–1.03)

0.07

1.01 (0.99–1.03)

0.22

Surgery

 LPS vs LPT

0.82 (0.35–1.89)

0.64

–

–

Morcellation

 Yes vs No

1.01 (0.51–2.01)

0.98

–

–

Oophorectomy

 Yes vs No

0.92 (0.53–81.60)

0.78

–

–

RT

 Yes vs No

0.68 (0.29–1.58)

0.37

–

–

Regimen

 A based vs G based

0.49 (0.30–0.80)

0.004

0.37 (0.17–0.80)

0.01

  1. aThe reported values are the third and first quartiles of the variable distribution
  2. bHazard ratio for a 10 years increase in age
  3. HR hazard ratio, CI confidence interval, G gemcitabine, A anthracycline, RT radiotherapy
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Clinical Sarcoma Research

ISSN: 2045-3329